ERROR: Command errored out with exit status 1:
   command: /usr/bin/python3 /tmp/tmpddkfb8u5_in_process.py get_requires_for_build_wheel /tmp/tmpu1r8grox
       cwd: /tmp/pip-install-tum9nqc8/mysqlclient_b0744843797d48b5842e6b1fca1f8603
  Complete output (24 lines):
  /bin/sh: 1: pkg-config: not found
  /bin/sh: 1: pkg-config: not found
  Trying pkg-config --exists mysqlclient
  Command 'pkg-config --exists mysqlclient' returned non-zero exit status 127.
  Trying pkg-config --exists mariadb
  Command 'pkg-config --exists mariadb' returned non-zero exit status 127.
  Traceback (most recent call last):
    File "/tmp/tmpddkfb8u5_in_process.py", line 280, in <module>
      main()
    File "/tmp/tmpddkfb8u5_in_process.py", line 263, in main
      json_out['return_val'] = hook(**hook_input['kwargs'])
    File "/tmp/tmpddkfb8u5_in_process.py", line 114, in get_requires_for_build_wheel
      return hook(config_settings)
    File "/tmp/pip-build-env-pwmm1fvu/overlay/lib/python3.9/site-packages/setuptools/build_meta.py", line 341, in get_requires_for_build_wheel
      return self._get_build_requires(config_settings, requirements=['wheel'])
    File "/tmp/pip-build-env-pwmm1fvu/overlay/lib/python3.9/site-packages/setuptools/build_meta.py", line 323, in _get_build_requires
      self.run_setup()
    File "/tmp/pip-build-env-pwmm1fvu/overlay/lib/python3.9/site-packages/setuptools/build_meta.py", line 338, in run_setup
      exec(code, locals())
    File "<string>", line 154, in <module>
    File "<string>", line 48, in get_config_posix
    File "<string>", line 27, in find_package_name
  Exception: Can not find valid pkg-config name.
  Specify MYSQLCLIENT_CFLAGS and MYSQLCLIENT_LDFLAGS env vars manually

apt install -y  libmariadb-dev-compat libmariadb-dev
pip install pymysql mysqlclient

其他
centos系统使用yum安装 mysql-devel

yum install mysql-devel

ubuntu 系统apt-get 安装libmysqlclient-dev

apt-get update
apt-get upgrade
apt-get install libmysqlclient-dev